Index page for: Vitamin C in Health and Disease

Table of Contents History of vitamin C: a history of scurvy and vitamin C. Chemistry and biochemistry: an overview of ascorbic acid chemistry and biochemistry, antioxidant and prooxidant properties of vitamin C, the vitamin C radical and its reactions, vitamin C and redox cycling antioxidants, regeneration of vitamin C, protein glycation by the oxidation products of ascorbic acid, ascorbate membrane transport properties. Physiology and biomedical aspects: vitamin C as an antiatherogen - mechanisms of action, protection of human low-density lipoprotein from oxidative modification by vitamin C, diet and oxidative damage to DNA - the importance of ascorbate as an antioxidant, vitamin C, collagen biosynthesis and aging, oxidative stress and ascorbate in relation to risk for cataract and age-related maculopathy, antioxidant action of vitamin C in the lung, vitamin C and asthma, effect of vitamin C on leucocyte function and adhesion to endothelial cells. Nutrition and health: human metabolism and the requirement for vitamin C, vitamin C safety in human, vitamin C in prospective epidemiological studies, nitrogen oxides are important contributors to cigarette smoke-induced ascorbate oxidation, vitamin C and cigarette smoke exposure, vitamin C, smoking, and alcohol consumption. (Part contents).