Index page for: Fermentation Microbiology and Biotechnology, Second Edition

Table of Contents Fermentation Microbiology and Biotechnology: An Historical Perspective, M. El-Mansi, C.F.A. Bryce, B. S. Hartley, and A. L. Demain Fermentation: An ancient tradition The rise of fermentation microbiology Developments in metabolic and biochemical engineering Discovery of antibiotics and genetic engineering The rise and fall of single cell protein Fermentation biotechnology and the production of amino acids Impact of functional genomics, proteomics, metabolomics and bio-informatics on the scope and future prospects of fermentation microbiology and biotechnology Microbiology of Industrial Fermentation, M. El-Mansi and F.B. Ward Chemical synthesis of bacterial protoplasm/biomass The growth cycle Diauxic growth Growth yield in relation to carbon and energy of growth substrates Fermentation balances Efficiency of central metabolism Continuous cultivation of micro-organisms Current advances and innovations in the fermentation and pharmaceutical industry Microbial fermentations and the production of biopharmaceuticals Fermentation Kinetics, J. Nielsen Framework for kinetic models Mass balances for bioreactors Kinetic models Population models NEW!Microbial Synthesis of Primary Metabolites: Current Advances and Future Prospects, A. L. Demain and S. Sanchez Control of primary metabolism Approaches to strain improvements Production of primary metabolites Microbial Synthesis of Secondary Metabolites and Strain Improvement, I. S. Hunter The economics and scale of microbial product fermentations Different products need different fermentation processes Fed-batch culture, the paradigm for many efficient microbial processes Tactical issues for strain improvement programs Strain improvement: The random, empirical approach Strain improvement: The power of recombination in strain construction Directed screening for mutants with altered metabolism Recombinant DNA approaches to strain improvement for low- and medium-value products Strain improvement for high-value recombinant products Metabolic Analysis and Optimization of Microbial and Animal Cell Bioprocesses, D. M. Mousdale Metabolic analysis in the era of genomics, proteomics, and metabolomics Secondary product fermentations Microbial production of industrial enzymes Animal cells and recombinant protein production in bioreactors Future prospects Flux Control Analysis: Basic Principles and Industrial Applications, M. El-Mansi and G. Stephanopoulos Introduction: traditional versus modern concepts Flux control analysis: basic principles Control of carbon flux at the junction of isocitrate in central metabolism during growth of Escherichia coli on acetate: a case study Modeling using other computer programs Strategies for manipulating carbon fluxes en route to product formation in intermediary metabolism Conversion of feedstock to biomass and desirable end products NEW!Enzyme and Co-factor Engineering and Their Applications in the Pharmaceutical and Fermentation Industries, G. N. Bennett and K.Y. San Types of major industrial enzymes and desired modifications Summary of methods in enzyme engineering Modification of pharmaceutical properties of protein agents Modification of enzymes for in vivo biosynthetic processes Co-factor engineering NEW!Application of Metabolic Engineering to the Conversion of Renewable Resources to Fuels and Fine Chemicals: Current Advances and Future Prospects, A. A. AristidouPentose fermentation Genetically engineered bacteria Genetically engineered yeast Microbes producing ethanol from lignocellulose NEW!Cell Immobilization and Its Applications in Biotechnology: Current Trends and Future Prospects, R. Willaert Immobilized cell systems Design of immobilized cell reactors Physiology of immobilized microbial cells Beer production using immobilized cell technology: A case study Biosensors in Bioprocess Monitoring and Control: Current Trends and Future Prospects, C. E. French and M. F. Cardosi Biosensors in process monitoring Overview of transduction methods Catalytic biosensors: Enzymes as biological sensing elements Affinity biosensors: Antibodies as biological detection elements Immobilization of the biological recognition element Amperometric biosensors based on redox enzymes Potentiometric biosensors and enzyme field effect transistor (ENFET) Thermal biosensors Optical biosensors based on redox enzymes Indirect affinity sensors: Optical and electrical biosensors based on antibodies Direct affinity detection using surface plasmon resonance and piezoelectric biosensors Amperometric glucose biosensors for blood glucose monitoring: A case study Fermentors: Design, Operation, and Applications, A. R. Allman Batch culture fermentation The main components of a fermentor and their uses Component parts of a typical vessel Peripheral parts and accessories Alternative vessel designs Different types of instrumentation Common measurement and control systems Additional sensors Simple continuous culture Additional accessories and peripherals Fermentor preparation and use Major types of organisms used in fermentation Subfermentor systems - a new approach Solutions to common problems in fermentation Control of Fermentations: An Industrial Perspective, C.J.L. Gershater Requirement for control Sensors Controllers Design of a fermentation control system Fermentor control specification Control of incubation Advanced incubation control Other advanced fermentation control options Recent trends in fermentation Control Modeling, Software Sensors, Control, and Supervision of Fermentation Processes, B. Dahhou, G. Roux, and Y. Nakkabi The model system Modeling Adaptive techniques Supervision for process control Appendix: Suppliers List Instrumentation, Sensors and Software Fermentation Equipment Index